Research Article
Rationalization of the Laboratory Diagnosis for Good Management of Malaria: Lessons from Transitional Methods
Table 3
Laboratory findings related to fever profile of the patients.
| | Distribution by age group of patients with positive malaria according to fever |
| | Age | Positive malaria with fever (%) | Positive malaria without fever (%) | Total size (%) | | 0–11 months | 120 (85.10) | 21 (14.89) | 141 (100) | | 1–4 years | 164 (80.40) | 40 (19.60) | 204 (100) | | 5–14 years | 39 (62.90) | 23 (37.10) | 62 (100) | | >15 years | 67 (25.09) | 200 (74.91) | 267 (100) | | Total | 390 | 284 | 674 (100) | | Predictive value of fever for malaria in patients between 0 and 11 months of age | | Fever | Positive malaria | Negative malaria | Total | | Present | 120 (a) | 158 (b) | 278 (a + b) | | Total | 141 (a + c) | 213 (b + d) | 334 (a + b + c + d) | | Sensitivity: a/(a + b) 120/278 = 0.43 (43%) | | Specificity: d/(c + d) 55/76 = 0.72 (72%) | | Positive predictive value: a/(a + c) = 120/141 = 0.85 (85%) | | Negative predictive value: d/(b + d) = 55/213 = 0.25 (25.82%) | | Predictive value of fever for malaria in patients between 1 and 4 years of age | | Fever | Positive malaria | Negative malaria | Total | | Present | 164 (a) | 161 (b) | 325 (a+b) | | Absent | 40 (c) | 73 (d) | 113 (c + d) | | Total | 204 (a + c) | 234 (b + d) | 438 (a +b + c + d) | | Sensitivity = 164/325 = 0.50 (50.46%) | | Specificity = 73/113 = 0.64 (64.60%) | | Positive predictive value = 164/204 = 0.80 (80.39%) | | Negative predictive value = 73/234 = 0.31 (31%) | | Predictive value of fever for malaria in patients between 5 and 15 years of age | | Fever | Positive malaria | Negative malaria | Total | | Present | 39 (a) | 63 (b) | 102 (a + b) | | Absent | 23 (c) | 57 (d) | 80 (c + d) | | Total | 62 (a + c) | 120 (b + d) | 182 (a + b + c + d) | | Sensitivity = 39/102 = 0.38 (38%) | | Specificity = 57/80 = 0.71 (71%) | | Positive predictive value = 39/62 = 0.63 (63%) | | Negative predictive value = 57/120 = 0.47 (47.5%) |
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