Efficiency of Automated Viral RNA Purification for Pediatric Studies of Dengue and Zika in Hyperendemic Areas

Table 1

Characteristics of the patients included in the study.

	Dengue suspected children n = 20	Plasma samples from healthy children experimentally infected or not with Zika n = 249
		Spiked positive; n = 40	Negative; n = 209
Gender (F/M)	10/10	24/16	83/126	0.323^a
Age (years)	11 (1–14)	8 (1–13)	10 (1–14)	0.09^b
Days of fever	3 (1–5)	N/A	N/A	N/A
DENV-1	7	—	ND	ND
DENV-2	5	—	ND	ND
DENV Negative	8	40	ND	ND

^aFisher’s exact test was used. ^bKruskal–Wallis test was applied. N/A: not applicable. ND: not done. RT-PCR positive and negative samples were also positive and negative for circulating NS1 as evaluated by ELISA.