Research Article
Association of Hematological and Biochemical Parameters with Serological Markers of Acute Dengue Infection during the 2022 Dengue Outbreak in Nepal
Table 2
Comparison of hematological and biochemical findings in NS1, IgM, and NS1 + IgM positive dengue patients.
| | Parameters | Dengue positive (n = 177) | | NS1 only (n = 83) | Both NS1 + IgM (n = 46) | IgM only (n = 48) | | Median (Q3–Q1) | Median (Q3–Q1) | Median (Q3–Q1) |
| | Hemoglobin (gm/dl) | 14.66 (15.87–12.90) | 14.32 (15.90–12.97) | 14.1 (14.7–12.62) | | RBC (X 1012/L) | 4.79 (5.3–4.24) | 4.72 (5.19–4.49) | 4.82 (5.09–4.42) | | HCT (%) | 41.4 (44.9–35.9) | 40.4 (45.42–37.7) | 40.65 (42.5–36.25) | | MCV (fl) | 86.5 (88.8–83.3) | 84.5 (88.12–80.2) | 83.7 (87.25–79.7) | | MCH (pg) | 30.7 (31.8–29.7) | 30.0 (31.32–28.2) | 29.25 (30.0–27.52) | | MCHC (gm/dl) | 35.5 (36–35.2) | 35.2 (35.82–3.5) | 34.75 (35.5–33.9) | | TLC (cells per µl) | 3880 (5790–2950) | 3345 (4442–2497) | 4800 (6525–3072) | | Neutrophil (%) | 67 (76–59) | 56.5 (67.75–46) | 55 (69–44.25) | | Lymphocyte (%) | 21 (30–14) | 33 (40–22) | 32.5 (46–20.25) | | Monocyte (%) | 9 (13–7) | 9.5 (12.25–6) | 7 (10.75–5.0) | | Eosinophil (%) | 1 (2–1) | 2 (3–1) | 1 (2–1) | | Platelets (per µl) | 164000 (192000–127000) | 113000 (153500–87000) | 131000 (177500–53500) | | NLR | 3.36 (5.61–1.97) | 1.83 (3.04–1.12) | 1.75 (3.5–1.00) | | LMR | 2.57 (3.77–1.46) | 3.25 (4.23–2.57) | 3.9 (6.12–2.34) | | Glucose (mg/dl) | 98.1 (117–86.0) | 104.5 (144.9–91.0) | 122 (173–90.9) | | Urea (mg/dl) | 21.78 (27.24–17.1) | 22.13 (31–17.64) | 30.04 (37.05–22.75) | | Creatinine (mg/dl) | 0.92 (1.17–0.76) | 0.82 (0.97–0.64) | 0.90 (0.99–0.72) | | Total bilirubin (mg/dl) | 0.49 (0.64–0.4) | 0.52 (0.7–0.4) | 0.51 (0.66–0.4) | | Direct bilirubin (mg/dl) | 0.1 (0.12–0.865) | 0.1 (0.2–0.08) | 0.1 (0.15–0.865) | | Total protein (gm/dl) | 7.06 (7.38–6.65) | 7.24 (7.56–6.89) | 6.95 (7.9–6.55) | | Albumin (gm/dl) | 4.03 (4.31–3.7) | 4.1 (4.31–3.86) | 4.1 (4.31–3.66) | | ALP (U/L) | 73.77 (129.6–61.07) | 106.4 (207.3–69.28) | 139.5 (192.5–90.72) | | AST (U/L) | 37.51 (56.23–28.06) | 76.27 (119.9–44.46) | 113 (197–36.75) | | ALT (U/L) | 30.64 (48.7–17.47) | 62.21 (98.9–36.0) | 92.42 (156.75–43.5) | | AST/ALT ratio | 1.29 (1.73–1.02) | 1.23 (1.58–1.06) | 1.17 (1.48–0.95) |
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RBC, red blood cell; HCT, hematocrit; MCV, mean cell volume; MCH, mean cell hemoglobin; MCHC, mean cell hemoglobin concentration; TLC, total leukocyte count; NLR, neutrophil lymphocyte ratio; LMR, lymphocyte monocyte ratio; ALP, alkaline phosphatase; AST, aspartate aminotransferase; ALT, alanine aminotransferase.
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