Evaluation of the Inhibitory Effect of Moringa oleifera Leaves Methanolic Extract against In Vitro Growth of Several Babesia Species and Theileria equi and the In Vivo Growth of Babesia microti
Table 1
IC50 values of Moringa oleifera leaves evaluated for bovine Babesia and equine Babesia and Theileria parasites.
Organism
IC50 (µg/ml)a
MOL
DA
Zingiber officinale rhizomeb
Turmeric (Curcuma longa)c
Pomegranate (Punica granatum) peeld
B. bovis
45.29 ± 6.14
0.16 ± 0.02
588 ± 23.80
830 ± 78
154.45 ± 23.11
B. bigemina
19.16 ± 0.45
0.08 ± 0.003
14800 ± 1240
ND
40.90 ± 9.35
T. equi
137.49 ± 16.07
0.28 ± 0.01
39350 ± 1340
1405 ± 575
100 ± 16.20
B. caballi
9.29 ± 0.014
0.012 ± 0.003
356.05 ± 34.71
720 ± 90
77.27 ± 16.94
aThe final IC50s obtained represents the mean ± SD of values obtained from three separate experiments. b[9], c[10], d[11]. MOL, Moringa oleifera leaves methanolic extract. DA, diminazene aceturate. ND not detected.
