Performance Evaluation of Three Diagnostic Methods for Soil-Transmitted Helminth Infections among Schoolchildren in Amhara Region, Northwest Ethiopia
Table 3
Diagnostic performance of KK, MM, and STST in STH detection against the composite reference as a “gold” standard in Amhara region, northwest Ethiopia, 2022 (N = 403).
Diagnostic methods
STHs
Composite reference as a “gold” standard
K value
value
Pos
Neg
SN (95% CI)
SP (95% CI)
PPV
NPV (95% CI)
(N)
(N)
KK
Pos
115
0
87.1 (80.2–92.3)
100 (98.6–100)
100
95.1 (92.6–96.8)
0.901
≤0.001
Neg
17
271
MM
Pos
121
0
91.7 (85.6–95.6)
100 (98.6–100)
100
96.5 (94.1–98.0)
0.937
≤0.001
Neg
11
271
STST
Pos
123
0
93.2 (87.5–96.8)
100 (98.6–100)
100
97.1 (94.7–98.4)
0.948
≤0.001
Neg
9
271
Hookworm
KK
Pos
101
0
87.8 (80.4–93.2)
100 (98.7–100)
100
95.4 (92.7–97.1)
0.912
≤0.001
Neg
14
288
MM
Pos
112
0
97.4 (92.6 99.5)
100 (98.7–100)
100
98.9 (96.9–99.6)
0.982
≤0.001
Neg
3
288
STST
PosNeg
106
0
92.2 (85.7–96.4)
100 (98.7–100)
100
97.0 (94.5–98.4)
0.944
≤0.001
9
288
KK = Kato-katz, MM = McMaster, Neg = negative, NPV = negative predictive value, Pos = positive, PPV = positive predictive value, K = Kappa, Se = sensitivity, Sp = specificity, STST = spontaneous tube sedimentation.
