Antibacterial and Antioxidant Efficacies of Secondary Metabolites from the Roots of Cyphostemma adenocaule: A Combined In Vitro and In Silico Study

Table 8

In silico drug-likeness properties of the isolated compounds (1–6) generated by SwissADME.

Compound no.	MF	MW (g/mol)	NRB	NHA	NHD	LogP (iLogP)	TPSA (Å^2)	Violation (Lipinski’s rule of five)
1	C29H50O	414.71	6	1	1	4.79	20.23	1
2	C20H30O3	318.45	0	3	1	2.92	46.53	0
3	C28H22O6	454.47	4	6	5	2.41	110.38	0
4	C15H10O8	318.24	1	8	6	1.08	151.59	1
5	C28H24O7	472.49	4	7	6	2.04	130.61	1
6	C28H22O6	454.47	3	6	6	2.25	121.38	1
Ciprofloxacin	C17H18FN3O3	331.34	3	5	2	2.24	74.57	0

MF, molecular formula; MW, molecular weight; NHA, number of hydrogen acceptors; NHD, number of hydrogen donors; NRB, number of rotatable bonds; TPSA, total polar surface area.