Research Article

Exenatide Pretreatment Improved Graft Function in Nonhuman Primate Islet Recipients Compared to Treatment after Transplant Only

Figure 4

Acute insulin response to glucose ( U/ml) as a measurement of first phase insulin secretion following i.v. glucose administration (a). Beta cell function as determined by homeostasis model assessment (HOMA-%B) (b). Untreated animals and animals treated with exenatide after transplant only were tested at day 0 and at day 10. ATG/CSA/MMF and exenatide pre-treatment groups were tested at day 0 and day 90.
382518.fig.004a
(a)
382518.fig.004b
(b)