Exenatide Pretreatment Improved Graft Function in Nonhuman Primate Islet Recipients Compared to Treatment after Transplant Only
Figure 4
Acute insulin response to glucose (U/ml) as a measurement of first phase insulin secretion following i.v. glucose administration (a). Beta cell function as determined by homeostasis model assessment (HOMA-%B) (b). Untreated animals and animals treated with exenatide after transplant only were tested at day 0 and at day 10. ATG/CSA/MMF and exenatide pre-treatment groups were tested at day 0 and day 90.