Clinical Study
Evaluation of Protocol Biopsy Utility 12 Months after Renal Transplantation: A Multicenter Observational Analysis
Table 4
Histological results of surveillance biopsies at one year posttransplant (central reading) among adequate samples ().
| | Histological lesions | Grade | (%) |
| | No significant changes (normal kidney graft) | | 51 (44) | | Acute antibody-mediated rejection | | 0 | | Chronic antibody-mediated rejection | | 2 (1.8) | | Acute cellular rejection | I B | 2 (1.8) | | Chronic cellular rejection | | 2 (1.8) | | C4d+ | | 3 (3) |
| | Glomerulitis (g) | 0 | 102 (87.9) | | 1 | 8 (6.9) | | 2 | 4 (3.4) | | 3 | 2 (1.7) |
| | Peritubular capillaritis (ptc) | 0 | 98 (85.2) | | 1 | 9 (7.8) | | 2 | 7 (6.1) | | 3 | 1 (0.9) |
| | Acute tubular necrosis | | 12 (10.3) | | IF/TA (Grade II and III) | | 35 (30.2) | | CNI-related toxicity | | 15 (12.9) | | Recurrence of initial disease | | 2 (1.7) | | BK virus nephropathy | | 1 (0.9) | | Thrombotic microangiopathy | | 3 (2.6) |
|
|
IF/TA: interstitial fibrosis/tubular atrophy.
|
