Research Article

New Onset Diabetes Mellitus in Living Donor versus Deceased Donor Liver Transplant Recipients: Analysis of the UNOS/OPTN Database

Table 1

Baseline demographic statistics for DDLT and LDLT recipients.

Variables
DDLT
( )
LDLT
( )
value

Recipient age, (%)
506652 (34)386 (42.8) 0.0001
5012930 (66)516 (57.2)
Recipient gender, (%)
 Female6350 (32.4)405 (44.9) 0.0001
 Male13232 (67.6)497 (55.1)
Recipient race, (%)
 Caucasian14377 (73.4)761 (84.4) 0.0001
 African American1784 (9.1)32 (3.5)
 Hispanic2320 (11.8)76 (8.4)
 Others1101 (5.6)33 (3.7)
Recipient BMI, (%)
256154 (32.9)396 (45.7) 0.0001
 25–306800 (36.3)299 (34.5)
305761 (30.8)171 (19.7)
Etiology of liver disease, (%)
 ALD2481 (12.7)78 (8.6) 0.0001
 ALF1070 (5.5)24 (2.7)
 HCV9837 (50.2)324 (35.9)
 NASH646 (3.3)17 (1.9)
 Others5548 (28.3)59 (50.9)
MELD score
 Mean (SD)20.9 (9.8)14.6 (5.3) 0.0001
Donor age, (%)
408754 (44.7)508 (56.4) 0.0001
 40–607926 (39.5)380 (42.3)
613102 (15.8)13 (1.4)
Donor gender, (%)
 Female7876 (40.2)446 (49.4) 0.0001
 Male11706 (59.8)456 (50.6)
Donor race, (%)
 Caucasian13304 (67.9)766 (84.9) 0.0001
 African American3094 (15.8)26 (2.9)
 Hispanic 2567 (13.1)81 (9)
 Others617 (3.2)29 (3.2)
Cold ischemia time, (%)
6 h6385 (32.6)658 (93.2) 0.0001
 6–12 h11105 (56.7)12 (1.7)
12 h839 (4.6)36 (5.1)
Episode of rejection, (%)
 Yes (with treatment)967 (4.9)33 (3.7)0.1267
 Yes (no treatment)250 (1.3)9 (1)
 No17265 (88.2)807 (89.4)
 Missing1100 (5.6)53 (5.9)
Steroid induction, (%)
 Yes10780 (55)650 (72) 0.0001
 No7141 (36.5)227 (25.2)
 Missing1661 (8.5)25 (2.8)
Calcineurin inhibitor use, (%)
 Yes18806 (96)881 (97.7)0.0159
 No776 (4)21 (2.3)
Patient survival time (days)
 Mean (SD)954.5 (608.5)1082.5 (642.6) 0.0001

DDLT: deceased donor liver transplant; LDLT: living donor liver transplant; BMI: body mass index; ALD: alcohol liver disease; ALF: acute liver failure; HCV: hepatitis C virus; NASH: nonalcoholic steatohepatitis; MELD: model for end-stage liver disease.