New Onset Diabetes Mellitus in Living Donor versus Deceased Donor Liver Transplant Recipients: Analysis of the UNOS/OPTN Database

Table 2

Association of risk factors for development of NODAT for all LT recipients (𝑛=20, 484).

Variable		Univariate; HR (95% CI)	𝑃 value	Multivariate; HR (95% CI)	𝑃 value
Donor type	Living versus deceased	0.55 (0.46–0.65)	<0.0001	0.63 (0.52–0.75)	<0.0001
Recipient age	>50 versus ≤50	1.23 (1.22–1.38)	<0.0001	1.14 (1.07–1.22)	0.0002
Recipient gender	Male versus female	1.16 (1.10–1.24)	<.0001	1.13 (1.06–1.20)	0.0003
Recipient race	AA versus others	1.91 (1.03–1.38)	0.021	1.07 (0.92–1.26)	0.3833
	Caucasian versus others	1.03 (0.91–1.17)	0.654	0.95 (0.84–1.09)	0.485
	Hispanic versus others	1.17 (1.01–1.35)	0.038	1.05 (0.90–1.22)	0.526
Recipient BMI	>30 versus ≤25	1.36 (1.26–1.46)	<0.0001	1.27 (1.18–1.37)	<0.0001
	25–30 versus ≤25	1.20 (1.12–1.28)	<0.0001	1.15 (1.07–1.23)	0.0002
Donor age	≥60 versus <60	1.26 (1.19–1.35)	<0.0001	1.21 (1.12–1.30)	<0.0001
Etiology of liver disease	ALD versus others	1.33 (1.20–1.46)	<0.0001	1.26 (1.13–1.40)	<0.0001
	HCV versus others	1.46 (1.36–1.57)	<0.0001	1.38 (1.27–1.49)	<0.0001
	NASH + cryptogenic cirrhosis versus others	1.58 (1.42–1.77)	<0.0001	1.47 (1.31–1.65)	<0.0001
Rejection	Treated rejection versus no rejection	3.35 (3.06–3.65)	<0.0001	3.50 (3.2–3.84)	<0.0001