Circulating CD4+CD28null T Cells May Increase the Risk of an Atherosclerotic Vascular Event Shortly after Kidney Transplantation
Table 2
Univariate and multivariate analysis of clinical and demographic parameters in association with the incidence of an atherosclerotic vascular event within the first year after kidney transplantation.
Univariate analysis
Multivariate analysis
Hazard ratio (95% confidence interval)
value
value
Male gender
0.56
0.13
—
Age (years)
0.02
0.61
1.01 (0.95–1.07)
Years of dialysis treatment
0.51
0.42
—
Non-Western European origin
0.47
0.83
—
History of atherosclerotic disease
<0.001
0.01
13.9 (1.7–113.5)
Diabetes mellitus
0.53
0.75
—
Smoking
0.19
0.22
—
Dyslipidemia
0.01
0.12
4.7 (1.71–13.22)
Hypertension
0.38
0.44
—
% CD4+CD28null T cells
0.01
0.05
1.04 (1.00–1.09)
% CD4+CD28null T cells* history of atherosclerotic disease
—
0.001
1.07 (1.03–1.11)
Interaction between the terms % CD4+CD28null T cells and a history of atherosclerotic disease on the incidence of an atherosclerotic event after kidney transplantation.
