Risk-Adjusted Analysis of Relevant Outcome Drivers for Patients after More Than Two Kidney Transplants

Table 2

The univariate influences of the investigated variables on patient survival are shown.

Recipient variables	value	Hazard ratio	95% confidence interval
Recipient sex	0.191	n.a.	n.a.
Recipient blood group	0.547	n.a.	n.a.
Age in years at last transplantation	0.016	1.068	1.012–1.128
Number of kidney transplants	0.583	n.a.	n.a.
PRA max. in %	0.231	n.a.	n.a.
PRA max. in groups (0–30%, >30–70%, and >70%)	0.386	n.a.	n.a.
PRA at last transplant in %	0.607	n.a.	n.a.
PRA at last transplant in groups (0–30%, >30–70%, and >70%)	0.578	n.a.	n.a.
Number of HLA-DR mismatches	0.918	n.a.	n.a.
Number of all HLA mismatches	0.656	n.a.	n.a.
Number of all HLA mismatches in groups (0–2, 3–6)	0.348	n.a.	n.a.
Plasmapheresis (yes/no)	0.719	n.a.	n.a.
Induction therapy (yes/no)	0.321	n.a.	n.a.
Type of induction therapy	0.180	n.a.	n.a.
Cyclosporine versus tacrolimus based therapy	0.066	n.a.	n.a.
Mycophenolate mofetil versus azathioprine therapy	0.430	n.a.	n.a.
Living donor versus deceased donor	0.482	n.a.	n.a.
Simultaneous nephrectomy of previous graft (yes/no)	0.532	n.a.	n.a.
Number of previous operations at transplant site	0.265	n.a.	n.a.
Operating time in minutes	0.359	n.a.	n.a.
Cold ischemic time in minutes	0.632	n.a.	n.a.
Surgical complications (yes/no)	0.294	n.a.	n.a.
Number of surgical complications	0.029	2.275	1.088–4.757
Reoperation due to a complication (yes/no)	0.054	n.a.	n.a.
Primary graft non-function (yes/no)	0.998	n.a.	n.a.
Acute graft rejection episodes (yes/no)	0.267	n.a.	n.a.
Chronic graft rejection (yes/no)	0.487	n.a.	n.a.
Graft loss (yes/no)	0.563	n.a.	n.a.

Univariate Cox regression analysis, n.a. = not applicable.