Clinical Study
A Single Perioperative Injection of Dexamethasone Decreases Nausea, Vomiting, and Pain after Laparoscopic Donor Nephrectomy
Table 1
Donor baseline variables and surgical outcomes.
| | Control
| Low dose dexamethasone
| High-dose dexamethasone
| values | values | Control versus low dose | Control versus high dose |
| Age (years) | 43.6 ± 13.4 | 41.7 ± 13.0 | 40.5 ± 12.5 | 0.34 | 0.09 | Sex | | | | <0.001 | 0.56 | Male | 51 (45.9) | 13 (18.6) | 42 (42.0) | | | Female | 60 (54.1) | 57 (81.4) | 58 (58.0) | | | BMI (kg/m2) | 26.5 ± 3.4 | 25.8 ± 4.1 | 26.7 ± 3.7 | 0.31 | 0.65 | ASA | | | | 0.18 | 0.21 | 1 | 77 (69.4) | 55 (78.6) | 77 (77.0) | | | 2 | 34 (30.6) | 15 (21.4) | 23 (23.0) | | | Intraoperative ondansetron use | 103 (92.8) | 64 (91.4) | 93 (93.0) | 0.74 | 0.95 | Operative time (min) | 147.8 ± 25.0 | 148.1 ± 22.7 | 155.4 ± 24.1 | 0.93 | 0.009 | Side of nephrectomy | | | | 0.013 | 0.85 | Left | 91 (81.1) | 46 (65.7) | 82 (82.0) | | | Right | 20 (18.9) | 24 (34.3) | 18 (18.0) | | | Postoperative hospital stay (days) | 2.68 ± 0.62 | 2.63 ± 0.59 | 2.66 ± 0.62 | 0.69 | 0.86 | Complications (%) | 3 (2.7) | 3 (4.3) | 0 (0) | 0.68 | 0.25 |
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Data are expressed as mean ± SD or (%). ASA: American Society of Anesthesiologists; BMI: body mass index.
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