Journal of Transplantation / 2017 / Article / Tab 1 / Research Article
Risk Balancing of Cold Ischemic Time against Night Shift Surgery Possibly Reduces Rates of Reoperation and Perioperative Graft Loss Table 1 Univariable binary regression of circadian risk development for binary output variables. Shown are the results of univariable regression analyses of the circadian risk development per 3-hour day and night shift intervals for the investigated endpoints hospital discharge on dialysis [Yes/No] , delayed graft function [Yes/No], early postoperative graft loss [Yes/No] , postoperative graft loss due to surgical reasons [Yes/No] , and reoperation [Yes/No]. Values of calculated odds ratios of each time interval were plotted on radar-plots to visualize the circadian risk developments of each investigated endpoint.
3 h interval No Yes % Univariable binary regression Circadian risk development OR 95% CI Reoperation 12 AM–3 AM 81 15 15.6 0.657 0.878 0.496–1.555 0.653 3 AM–6 AM 17 8 32 0.056 2.301 0.980–5.402 0.070 6 AM–9 AM 117 17 12.7 0.140 0.670 0.394–1.140 0.124 9 AM–12 PM ( 229 38 14.2 0.140 0.751 0.514–1.098 0.131 12 AM–3 PM 226 48 17.5 0.904 1.022 0.718–1.454 0.904 3 PM–6 PM 136 33 19.5 0.406 1.191 0.789–1.798 0.412 6 PM–9 PM 133 24 15.3 0.482 0.847 0.534–1.344 0.475 9 PM–12 AM 105 35 25.0 0.011 1.710 1.131–2.588 0.014 3 h interval No Yes % Univariable binary regression Circadian risk development OR 95% CI Perioperative graft loss 12 AM–3 AM 94 2 2.1 0.269 0.447 0.107–1.862 0.211 3 AM–6 AM 21 4 16.0 0.008 4.430 1.467–13.38 0.024 6 AM–9 AM 129 5 3.7 0.707 0.836 0.327–2.133 0.701 9 AM–12 PM 259 8 3.0 0.224 0.623 0.291–1.335 0.200 12 PM–3 PM 262 12 4.4 0.984 1.007 0.523–1.937 0.984 3 PM–6 PM 159 10 5.9 0.289 1.465 0.724–2.965 0.307 6 PM–9 PM 151 6 3.8 0.725 0.856 0.361–2.033 0.720 9 PM–12 AM 132 8 5.7 0.407 1.386 0.641–2.997 0.423 3 h interval No Yes % Univariable binary regression Circadian risk development OR 95% CI Perioperative graft loss due to surgical reasons 12 AM–3 AM 95 1 1 0.616 0.597 0.079–4.496 0.588 3 AM–6 AM 22 3 12 0.001 9.242 2.537–33.67 0.007 6 AM–9 AM 131 3 2.2 0.583 1.413 0.411–4.863 0.598 9 AM–12 PM 265 2 0.7 0.205 0.388 0.090–1.677 0.151 12 PM–3 PM 269 5 1.8 0.813 1.130 0.410–3.113 0.815 3 PM–6 PM 166 3 1.8 0.902 1.080 0.315–3.708 0.903 6 PM–9 PM 157 0 0 0.996 0.000 0.000 0.018 9 PM–12 AM 136 4 2.9 0.249 1.913 0.635–5.769 0.281 3 h interval No Yes % Univariable binary regression Circadian risk development OR 95% CI Delayed graft function 12 AM–3 AM 48 25 34.2 0.441 1.220 0.735–2.026 0.445 3 AM–6 AM 12 3 20.0 0.388 0.571 0.160–2.040 0.364 6 AM–9 AM 68 31 31.3 0.812 1.056 0.672–1.660 0.812 9 AM–12 PM 137 49 26.3 0.188 0.783 0.544–1.127 0.183 12 PM–3 PM 121 60 33.1 0.345 1.184 0.834–1.681 0.347 3 PM–6 PM 82 30 26.8 0.389 0.822 0.526–1.284 0.384 6 PM–9 PM 76 29 27.6 0.527 0.863 0.548–1.361 0.524 9 PM–12 AM 57 34 37.4 0.121 1.429 0.910–2.246 0.126 3 h interval No Yes % Univariable binary regression Circadian risk development OR 95% CI Discharge on dialysis 12 AM–3 AM 73 4 5.1 0.119 0.441 0.158–1.233 0.081 3 AM–6 AM 15 4 21.1 0.145 2.305 0.750–7.082 0.178 6 AM–9 AM 99 15 13.2 0.342 1.329 0.739–2.389 0.354 9 AM–12 PM 186 21 10.1 0.818 0.942 0.568–1.564 0.817 12 PM–3 PM 181 19 9.5 0.577 0.861 0.510–1.456 0.572 3 PM–6 PM 112 15 11.8 0.629 1.155 0.645–2.068 0.633 6 PM–9 PM 105 9 7.9 0.323 0.698 0.342–1.425 0.303 9 PM–12 AM 91 15 14.2 0.208 1.461 0.810–2.634 0.223
