Research Article

Renal Transplants from Older Deceased Donors: Use of Preimplantation Biopsy and Differential Allocation to Dual or Single Kidney Transplant according to Histological Score Has No Advantages over Allocation to Single Kidney Transplant by Simple Clinical Indication

Table 3

Characteristics of recipients from donors older than 60 years according to period and transplant category and main transplant characteristics and outcomes. Data are numbers, mean ± SD, or median (ranges).

PeriodPre-DKTDKT era

Tx categoryDKT
170335148
M/F115/5526/736/1534/14
Age, years59 ± 7.458.5 ± 8.763.5 ± 5.766.7 ± 4.5
Months on dialysis45 (6–298)50 (11–216)37 (5–107)29 (4–226)
1st-2nd-3rd Tx, 152-15-329-4-050-0-1+48-0-0+
HLA-MM4 (0–6)4 (1–6)4 (1–6)5 (3–6)
Follow-up, months/pt72.0 (62.6–72.0)44.1 (34.0–62.0)43.3 (24.2–59.4)44.2 (26.0–64.3)
Total follow-up, pt-yrs827.4126.7169.6176.0
CIT, hrs:min13:58 ± 4:0814:04 ± 4:5616:27 ± 3:5316:05 ± 3:26
PNF, . (surg)8 (4)16 (2)2 (2)
PNF, %4.73.011.74.2
DGF, (%)72 (42.3)20 (60.6)25 (49,0)23 (47.9)
BPR-18mo, (%)13 (7.6)4 (12.1)10 (20.8)+4 (8.3)
Graft failure, (/100 pt-yr)21 (2.5)3 (2.4)10 (5.9)+4 (2.3)
Death, ( pt-yr)24 (2.9)2 (1.6)7 (4.1)5 (2.8)

Pre-DKT, DKT era: see Table 2. Mismatches on HLA loci A, B and DRB1; time to event or censoring; cold ischemia time; graft primary nonfunction (number of surgical failures in parenthesis); Delayed graft function (need for dialysis in the first week post-Tx); biopsy-proven rejection within 18 months after transplant; PNF and graft losses over time. Statistical differences: < 0.01 versus and ; +P < 0.05 versus ; P < 0.05 or less versus all other categories.