Natural Antibodies and Alloreactive T Cells Long after Kidney Transplantation

Table 1

Patient characteristics.

	Without rejection, n = 110	With rejection, n = 35	value
At transplantation
Recipient age (median)	55 (44–63)	58 (44–65)	0.26
Recipient gender (% male)	77 (69%)	20 (57%)	0.22
Living donors (%)	85 (77%)	30 (86%)	0.34
Deceased donors (%)	25 (23%)	5 (14%)	0.34
Heart beating deceased donors (%)	9/25	5/5	0.28
Donor age (mean±SD)	49 ± 10	60 ± 14	<0.0001
First transplants (%)	102 (92%)	27 (77%)	0.03
At 5–7 years after transplantation
Anti-HLA antibodies (% present)^a	13 (14%)	11 (31%)	0.05
DSA (% present)^a	6 (7%)	1 (3%)	1.0
Serum creatinine (µmol/l)	120 (100–141)	152 (127–211)	<0.0001
Tacrolimus trough level (ng/ml)	5.4 (4.7–6.3)	5.8 (4.8–7.6)	0.08
Graft failure at Aug 1, 2021 (%)	4 (4%)	4 (11%)	0.10

^aAnti-HLA antibodies or DSA determined by Luminex.