The Evaluation of Tau Deposition with [<sup>18</sup>F]PI-2620 by Using a Semiquantitative Method in Cognitively Normal Subjects and Patients with Mild Cognitive Impairment and Alzheimer’s Disease

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left"></td><td class="align_center">Cognitively normal individuals</td><td class="align_center">Mild cognitive impairment patients</td><td class="align_center">Alzheimer’s disease patients</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">Number</td><td class="align_center">26</td><td class="align_center">36</td><td class="align_center">7</td></tr><tr><td class="align_left">Age: <svg height="9.10327pt" id="M17" style="vertical-align:-0.3499298pt" version="1.1" viewbox="-0.0498162 -8.75334 58.1969 9.10327" width="58.1969pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M797 0V26C739 32 732 36 732 103V296C732 394 682 449 605 449C576 449 550 437 529 423C504 407 475 389 446 366C425 418 382 449 334 449C303 449 279 437 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337C318 337 361 256 361 173C361 105 336 22 258 22C176 22 126 120 126 240C126 266 127 291 132 310C155 323 189 337 227 337Z"></path></g><g transform="matrix(.013,0,0,-0.013,47.609,0)"><path d="M113 -12C146 -12 170 11 170 46C170 78 146 103 114 103S58 78 58 46C58 11 82 -12 113 -12Z"></path></g><g transform="matrix(.013,0,0,-0.013,50.573,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,56.813,0)"><path d="M244 635C114 635 38 519 38 422C38 317 111 240 217 240C236 240 255 244 277 256L345 292C311 140 203 39 59 15L64 -15C89 -15 150 -5 204 17C339 72 440 202 440 386C440 521 368 635 244 635ZM228 602C326 602 352 479 352 390C352 370 351 347 348 324C327 308 293 296 258 296C174 296 124 369 124 458C124 517 152 602 228 602Z"></path></g></svg> (59-74)</td></tr><tr><td class="align_left">Gender (%)</td><td class="align_left"></td><td class="align_left"></td><td class="align_left"></td></tr><tr><td class="align_left"> Men: number (%)</td><td class="align_center">8 (30%)</td><td class="align_center">11 (30%)</td><td class="align_center">3 (43%)</td></tr><tr><td class="align_left"> Women: number (%)</td><td class="align_center">18 (70%)</td><td class="align_center">25 (70%)</td><td class="align_center">4 (57%)</td></tr><tr><td class="align_left">Education years: mean (range)</td><td class="align_center">13.4 (0-21)</td><td class="align_center">10.7 (0-18)</td><td class="align_center">11.0 (4-16)</td></tr><tr><td class="align_left">MMSE: mean (range)</td><td class="align_center">27.3 (26-30)</td><td class="align_center">26.1 (20-30)</td><td class="align_center">18.4 (12-23)</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Participants’ characteristics.</div>

Molecular Imaging

tab1

Table 1

Table 1: The Evaluation of Tau Deposition with [<sup>18</sup>F]PI-2620 by Using a Semiquantitative Method in Cognitively Normal Subjects and Patients with Mild Cognitive Impairment and Alzheimer’s Disease 

Table 1 | The Evaluation of Tau Deposition with [18F]PI-2620 by Using a Semiquantitative Method in Cognitively Normal Subjects and Patients with Mild Cognitive Impairment and Alzheimer’s Disease 