[¹⁸F]PARPi Imaging Is Not Affected by HPV Status In Vitro

Figure 6

[¹⁸F]PARPi uptake in HPV-negative and HPV-positive cell lines. (a) In vitro internalization assay of 370 kBq of [¹⁸F]PARPi showing significant specific tracer uptake. Uptake was blocked using 100-fold excess Olaparib 1 h before adding [¹⁸F]PARPi. (b) Quantification of total uptake in relation to HPV status showing no significant difference of HPV-negative and HPV-positive cell lines (, , , Student -test).

(a)

(b)