Celecoxib-Induced Modulation of Colon Cancer CD133 Expression Occurs through AKT Inhibition and Is Monitored by <sup>89</sup>Zr Immuno-PET

<div>Colon cancer cell binding and pharmacokinetic properties of <sup>89</sup>Zr-CD133 IgG. (a) Western blotting of CD133 protein in various colon cancer cell lines (top) and <sup>89</sup>Zr-CD133 IgG binding to high-expressing HT29 and low-expressing HCT116 human colon cancer cells (bottom). (b) Specificity of binding was assessed by blocking with excess cold anti-CD133 IgG. 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Molecular Imaging

fig2

Figure 2

Figure 2: Celecoxib-Induced Modulation of Colon Cancer CD133 Expression Occurs through AKT Inhibition and Is Monitored by <sup>89</sup>Zr Immuno-PET 

Molecular Imaging

Celecoxib-Induced Modulation of Colon Cancer CD133 Expression Occurs through AKT Inhibition and Is Monitored by 89Zr Immuno-PET

Figure 2

Celecoxib-Induced Modulation of Colon Cancer CD133 Expression Occurs through AKT Inhibition and Is Monitored by ⁸⁹Zr Immuno-PET