Research Article

89Zr Immuno-PET Imaging of Tumor PD-1 Reveals That PMA Upregulates Lymphoma PD-1 through NFκB and JNK Signaling

Figure 5

PET/CT imaging of tumor 89Zr-PD-1 IgG uptake and effects of PMA stimulation. Representative maximum intensity projection images (a–c) and coronal (d–f) and transaxial PET images (g) of mice at baseline, with excess antibody blocking, and after PMA treatment at 6 days after intravenous 89Zr-PD-1 IgG. Arrows indicate EL4 tumors.