Research Article

High SUVs Have More Robust Repeatability in Patients with Metastatic Prostate Cancer: Results from a Prospective Test-Retest Cohort Imaged with 18F-DCFPyL

Figure 3

Correlation (first column), Bland-Altman for absolute values (second column) and Bland-Altman for relative values (third column) of quantitative parameters (first row, maximum standardized uptake values (SUVmax); second row, mean standardized uptake values (SUVmean); third row, PSMA-avid tumor volume (PSMA-TV); and fourth row, total-lesion PSMA (TL-PSMA)). Good correlations were found for all parameters. Relative to SUV, volumetric parameters demonstrated larger magnitude of limits as presented by standard deviations on Bland-Altman plots for both absolute and relative values. The wide distribution of SUVs included in this analysis allowed for the demonstration of a dependence of repeatability on SUV, with higher SUVs having more robust repeatability, in particular for relative SUVmax values (top right).