In Vivo Distribution and Therapeutic Efficacy of Radioiodine-Labeled pH-Low Insertion Peptide Variant 3 in a Mouse Model of Breast Cancer

<div>Fluorescence imaging and cell viability at different pH values. Fluorescence imaging (×100) demonstrated that the ability of (a) FITC-labeled variant 3 pH-low insertion peptide (var3-pHLIP) and (b) FITC-labeled wild-type (WT)-pHLIP to bind to MDA-MB-231 cell line increased with the decrease in pH (7.8, 7.4, 7.0, 6.6, and 6.2).</div>

Molecular Imaging

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Figure 1

Figure 1: In Vivo Distribution and Therapeutic Efficacy of Radioiodine-Labeled pH-Low Insertion Peptide Variant 3 in a Mouse Model of Breast Cancer 