Research Article
First-in-Human PET Imaging of [18F]SDM-4MP3: A Cautionary Tale
Table 1
Participant information and injection parameters.
| | Participant | [18F]SDM-4MP3 | [18F]SynVesT-1 | | P1 | P2 | P3 | P4 |
| | Age () | 70 | 44 | 50 | 67 | | Sex | F | F | F | M | | Body weight (kg) | 89.8 | 54 | 90 | 73.5 | | Smoking status | Nonsmoker | Non-smoker | Non-smoker | Non-smoker | | Medications | Levothyroxine, rosuvastatin, hydrochlorothiazide | None | Amitryptyline | None | | Injected dose (MBq) | 189.00 | 196.36 | 182.68 | 185.87 | | Molar activity at injection (TBq/mmol) | 272.8 | 138.9 | 221.3 | 99.1 | | Injected mass (μg) | 0.209 | 0.427 | 0.250 | 0.567 |
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