Research Article

Recursive Gaussian Process Regression Model for Adaptive Quality Monitoring in Batch Processes

Table 1

Process variables used in the modeling of the fed-batch penicillin process.

NumberMeasured variables

1Aeration rate (L/h)
2Agitator power (W)
3Substrate feed rate (L/h)
4Substrate feed temperature (K)
5Dissolved oxygen concentration (g/L)
6Carbon dioxide concentration (g/L)
7pH
8Fermenter temperature (K)
9Generated heat (kcal)
10Cooling water flow rate (L/h)
11Culture volume (L)