Identification of Molecular Mechanism of OSA with Hypertension Based on Multiple Microarray Analysis

Figure 6

Using GSVA to investigate the specific signaling pathways involved in the three core genes and to explore the potential molecular mechanisms by which the core genes affect disease progression. (a) High expression of GPR179 gene was associated with MYOGENESIS, ANGIOGENESIS, OXIDATIVE_PHOSPHORYLATION, and XENOBIOTIC_ METABOLISM pathways. (b) High expression of JPH4 is associated with ANDROGEN_RESPONSE, ESTROGEN_RESPONSE_EARLY, and PI3K_AKT_MTOR_SIGNALING pathways. (c) High expression of RNF150 is associated with the MYC_TARGETS signaling pathway.

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