Stability and Hopf Bifurcation Analysis of an Oncolytic Virus Infection Model with Two Time Delays and Saturation Incidence

Table 1

Parameter of the system (1).

Parameters	Units	Defmitions
b^−1	mm^3	The maximum carrying capacity of tumor cell
β	Day^−1 mm^−3	The infection rate of tumor cells
C1	Day^−1	The clearance rate of CTLs to uninfected tumor cells
C2	Day^−1	The clearance rate of CTLs to infected tumor cells
d1	Day^−1 mm^−3	The mortality of infected tumor cells
d2	Day^−1 mm^−3	The mortality of virus
d3	Day^−1 mm^−3	The mortality of CTLs
k1	Day^−1 mm^−3	The maximum growth rate ofuninfected tumor cells
k2	Day^−1 mm^−3	The average rate at which the infected tumor cells release the virus
k3	Day^−1 mm^−3	Corresponding to the infection of uninfected tumor cells rate of CTLs simulation.
k4	Day^−1 mm^−3	Corresponding to the infection of infected tumor cells rate of CTLs simu lation
q	—	A constant greater than 0