Diffusion Tensor Imaging in NAWM and NADGM in MS and CIS: Association with Candidate Biomarkers in Sera
Figure 1
Region-of-interest (ROI) placement on axial FA colour maps. The posterior limb of the internal capsule (1, 2), the splenium (3), and the genu (4) of the corpus callosum (a); the posterior corona radiata anterior (1, 2) and posterior (3, 4) (b); the centrum semiovale anterior (c); and the caudate nucleus (1, 2) and the thalamus (3, 4) (d). Colours indicate the directions of fibre tracts (red, transverse; blue, craniocaudal; green, anterior-posterior). The circular ROIs were transferred from the corresponding image, and their sizes have been adjusted to avoid any visible lesions. The size of the ROIs ranged from 2 to 33 pixels (6–106.5 mm2; pixel size mm2) depending on the size of the brain structure. This figure is a representative analysis from an SPMS patient.