The Role of -Containing Kainate Receptors in Entorhinal Cortex Gamma Frequency Oscillations
Figure 3
Preincubation of slices in
UBP302 inhibits the ability of the MEC network to produce kainate-driven gamma frequency
oscillations. (a) Extracellular field recordings showing 1 second epochs of
activity (i) following preincubation with 10 μM UBP302, (ii) following application of 400 nM
kainate onto preincubated slices, and (iii) during a washout period into 400 nM
kainate. (b) Pooled power spectra (n = 11) produced from 60 second epochs of
extracellular field recorded data, showing a control recording (black), a
recording following 10 μM UBP302 preincubation (blue), 400 nM kainate
application following preincubation (green), and washout into 400 nM kainate
(red). Scale bar represents 200 milliseconds and 100 μV.
