The Role of -Containing Kainate Receptors in Entorhinal Cortex Gamma Frequency Oscillations
Figure 4
Activation of GLUK5-containing
KARs can induce gamma frequency oscillations in the MEC.
(a) Extracellular field
recordings showing 1 second epochs of activity in a control setting (i) following
application of 1 μM,
(ii) 2 μM
(iii), and 5 μM
ATPA (iv). (b) Pooled line graphs (n = 10) demonstrating the
effects of varying ATPA concentration on (i) frequency, (ii) area power, and
(iii) peak amplitude of gamma oscillations in the MEC. Scale
bar represents 200 milliseconds and 100 μV.