Research Article

The Role of NMDA Receptor Subtypes in Short-Term Plasticity in the Rat Entorhinal Cortex

Figure 3

Progressive changes associated with repeated episodes of stimulation at 3 Hz in the absence of NMDAr blockers. Each point is the degree of facilitation recorded during a 30-second period of stimulation and is the average from 5 neurones. (a) After an initial decline in the degree of facilitation, it remained stable throughout the subsequent 30 minutes of recording. (b) Mean amplitude of responses recorded at low and high frequency used to assess the facilitation in the neurones shown in (a). There was a progressive, albeit small increase in amplitude of responses in both cases. Representative records from one neurone, sampled at the times indicated, are shown below.
872456.fig.003a
(a)
872456.fig.003b
(b)
872456.fig.003c