Odorant Receptors Signaling Instructs the Development and Plasticity of the Glomerular Map

Figure 4

OSN in the OE that expresses the same type of OR projects axons to specific coordinates in the OB forming glomeruli. (a) The OB and the OE of a M72tLacZ mouse are shown (dorsal view). Neurons and axons that contain beta-galactosidase activity (blue) are revealed by X-gal. The M72 neurons, scattered throughout the OE, project their axons to the dorsal-posterior part of the OB and form at least one glomerulus. (b) OB coronal slice (20 m) of a M72tGFP mouse. The M72 glomerus, surrounded by periglomerular cells (stained with DAPI, blue), only contains axons (green) from the M72 OSN population.

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