Structural and Functional Deficits in Patients with Poststroke Dementia: A Multimodal MRI Study

Table 1

Demographic and clinical information of all participants.

	NCs ()	PSND ()	PSD ()		value
Age^†, mean (SD)	60.71 (10.36)	61.67 (7.21)	66.95 (9.04)	2.94	0.06
Male^‡, (%)	9 (43)	20 (83)	11 (55)	8.27	0.02
Handiness	R	R	R	N/A	N/A
ICV (L)^†, mean (SD)	1.46 (0.14)	1.41 (0.31)	1.30 (0.26)	8.35	0.02
FD^†, mean (SD)	0.09 (0.07)	0.11 (0.07)	0.08 (0.05)	5.16	0.08
Education level^‡, (%)				19.36	0.01
None	0	4 (17)	7 (35)
Primary	14 (67)	6 (25)	5(25)
Junior high school	5 (24)	8 (33)	5 (25)
Senior high school	2 (9)	5 (21)	3 (15)
Superior	0	1 (4)	0
Duration of illness (day)^†, mean (SD)	N/A	99.04 (62.14)	104.55 (69.69)	-0.28	0.78
NIHSS^1†, mean (SD)	N/A	1.79 (2.36)	1.55 (2.21)	0.35	0.73
NIHSS^2†, mean (SD)	N/A	0.17 (0.38)	0.25 (0.44)	-0.67	0.51
mRS^1‡, (%)				3.03	0.39
0-1-2-4	N/A	15 (63)-7 (29)-0-2 (8)	14 (70)-5 (25)-1 (5)-0
mRS^2‡, (%)				0.11	0.74
0-1	N/A	19 (79)-5 (21)	15 (75)-5 (25)
MMSE^1†, mean (SD)	25.88 (3.04)	26.88 (2.91)	20.30 (4.50)	20.77	<0.001
MMSE^2†, mean(SD)	25.88 (3.04)	27.17 (2.32)	20.45 (4.38)	24.19	<0.001
Mini-Cog^1‡, (%)				79.46	<0.001
0-1-2-3-4-5-6-7	0-0-0-0-1 (5)-5 (24)-3 (14)-12 (57)	0-0-3 (13)-12 (50)-0-9 (37)-0-0	2 (10)-0-7 (35)-9 (45)-2 (10)-0-0-0
Mini-Cog^1‡, (%)				65.34	<0.001
0-1-2-3-4-5-6-7	0-0-0-0-1 (5)-5 (24)-3 (14)-12 (57)	0-0-2 (8)-8 (33)-1 (5)-13 (54)-0-0	3 (15)-1 (5)-4 (20)-7 (35)-1 (5)-4 (20)-0-0

¹Acute phase; ²third month; ^†one-way ANOVA analysis/two-sample -test; ^‡chi-square test. Age, ICV, duration of illness, and MMSE are shown as mean (standard deviation); other data ( (%)) are number of participants (percentage). , , and represent , , and , respectively. NCs: normal controls; PSND: poststroke nondemented; PSD: poststroke demented; ICV: intracranial volume; FD: framewise displacement; NIHSS: National Institutes of Health Stroke Scale; mRS: modified Rankin Scale; MMSE: Mini-Mental State Examination.