Differential Proteomic Analysis of the Hippocampus in Rats with Neuropathic Pain to Investigate the Use of Electroacupuncture in Relieving Mechanical Allodynia and Cognitive Decline

Figure 2

Quantification of differentially expressed proteins in the three groups. (a) Number of differentially expressed protein using a threshold of 1.2-fold (EA group vs. SNI group; SNI group vs. Sham group). (b) Volcanic scatter plot with a threshold of 1.2-fold. (c) Number of EA-regulated SNI-induced differential proteins shown in the Venn diagram using a threshold of 1.2-fold. (d) Hippocampal TMEM126A expression detected with ELISA in the different groups (one-way ANOVA, , ; post hoc Tukey test, Sham group vs. SNI group, ^##; EA group vs. SNI group, ; per group). (e) Hippocampal TMEM126A expression detected via western blot in the different groups (one-way ANOVA, , ; post hoc Tukey test, Sham group vs. SNI group, ^##; EA group vs. SNI group, ; per group).

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