Differential Proteomic Analysis of the Hippocampus in Rats with Neuropathic Pain to Investigate the Use of Electroacupuncture in Relieving Mechanical Allodynia and Cognitive Decline

Table 1

Proteomic information and biological functions of TMEM126 and AEAAT2.

SNI vs. Sham most significant differential proteins	Transmembrane protein 126A	Excitatory amino acid transporters (SLC1A2/EAAT2)
Change ratio	0.64	4.681
value	0.0016	0.000000212
Subcellular localization	Cytoplasm	Plasma membrane
KEGG orthology	K18157	K05613
Main role of current reports	Immune-inflammatory and tumor metastasis regulation [22–24]	Clearance of spinal glutamate released in pain states; restore hippocampus-dependent memory deficit [25–28]