Research Article

A New Classification System for Postinterventional Cerebral Hyperdensity: The Influence on Hemorrhagic Transformation and Clinical Prognosis in Acute Stroke

Table 2

Demographic and clinical characteristics of the four subtypes of PCHD.

PCHD-1 ()PCHD-2 ()PCHD-3 ()PCHD-4 ()

Age0.900
Sex (male; %)8; 38.1%10; 58.8%22; 64.7%21; 58.3%0.271
Smoking3; 14.3%3; 17.6%6; 17.6%9; 25.0%0.763f
Hypertension17; 81.0%15; 88.2%27; 79.4%29; 80.6%0.875f
Atrial fibrillation11; 52.4%8; 47.1%19; 55.9%18; 50.0%0.934
Diabetes2; 9.5%1; 5.9%10; 29.4%9; 25.0%0.082f
Anticoagulant use5; 23.8%5; 29.4%11; 32.4%3; 8.3%0.063f
TC0.956
HDL0.633
LDL0.802
APTT0.487
PT0.390
Time of onset (h)0.647
NIHSS at admission0.219
ASPECT score5; 23.8%8; 47.1%24; 70.6%19; 52.8%0.009
OP (AC; %)16; 76.2%17; 100.0%28; 82.4%31; 86.1%0.077f
CT value (HU)0.002
Subarachnoid HD4; 19.0%1; 5.9%5; 14.7%4; 11.1%0.628f
Intraventricular HD0; 0.0%0; 0.0%1; 2.9%8; 22.2%0.002f
Operation time (h)0.726
VR (good, %)19; 90.5%15; 88.2%30; 88.2%28; 77.8%0.510f
Bridging treatment6; 28.6%9; 52.9%15; 44.1%14; 38.9%0.467
HT11; 52.4.0%9; 52.9%31; 91.2%33; 91.7%<0.001f
END5; 23.8%5; 29.4%14; 41.2%26; 72.2%0.001
3-month mRS12; 57.1%12; 70.6%31; 91.2%35; 97.2%<0.001f

TC: total cholesterol; HDL: high-density lipoprotein; LDL: low-density lipoprotein; APTT: activated partial thromboplastin time; PT: prothrombin time; OP: occluded position; AC: anterior circulation; HD: hyperdensity; VR: vascular recanalization; HT: hemorrhagic transformation; END: early neurological deterioration; f: Fisher’s exact test; : the CT value of the high-density PCHD-4 group was higher than that of the PCHD-1 and PCHD-2 groups, but no difference was found between these three subgroups and the PCHD-3 group.