Effect of Acupuncture Stimulation of Hegu (LI4) and Taichong (LR3) on the Resting-State Networks in Alzheimer’s Disease: Beyond the Default Mode Network

Table 2

Comparison of large-scale networks before acupuncture between AD patients and HCs.

Networks	Brain regions	MNI coordinate			BA	Cluster size	score
		lFPN	Left SFG	-30				60	21	10	44	5.77
Left MFG	-48		9	42	8	88	6.53
Left precuneus	-36		-78	36	19	34	4.65
Right IFG	45		6	39	9	37	5.73
Right MFG	3		24	48	8	28	5.28
Left SFG	-24		15	54	8	31	7.79
rFPN	Right AG	42	-60	54	40	63	6.1
	Right MFG	30	9	60	6	38	5.19
SMN	Left IPL	-42	-30	42	40	36	4.27
	Left PoCG	-36	-30	69	3	121	7.46
	Right PoCG	48	-36	60	40	63	5.35
	Right MFG	3	-27	63	6	57	4.94
VN	Right MOG	21	-99	0	18	752	8.5

FC: functional connectivity; AD: Alzheimer’s disease; HCs: healthy controls; BA: Brodmann area; MNI: Montreal Neurological Institute; , , and : coordinates of primary peak locations in the MNI space; lFPN: left frontal parietal network; rFPN: right frontal parietal network; SMN: sensorimotor network; VN: visual network; SFG: superior frontal gyrus; MFG: middle frontal gyrus; IFG: inferior frontal gyrus; AG: angular gyrus; IPL: inferior parietal lobule; PoCG: postcentral gyrus; MOG: middle occipital gyrus.