Effect of Acupuncture Stimulation of Hegu (LI4) and Taichong (LR3) on the Resting-State Networks in Alzheimer’s Disease: Beyond the Default Mode Network

Table 3

Brain regions with decreased or increased FC possibly related to acupuncture in the AD patients.

Networks	Brain regions	MNI coordinate			BA	Cluster size	score
			Decreased:
lFPN	Right cerebellum crus I	36	-63	39	—	111	5.37
	Left IFG	-45	30	-15	47	48	5.81
	Left AG	-39	-63	33	39	90	6.42
	Increased:
lFPN	Left MFG	-24	18	51	8	30	5.68
VN	Right LG	15	-72	-6	18	29	4.73

FC: functional connectivity; AD: Alzheimer’s disease; HCs: healthy controls; BA: Brodmann area; MNI: Montreal Neurological Institute; , , and : coordinates of primary peak locations in the MNI space; lFPN: left frontal parietal network; VN: visual network; IFG: inferior frontal gyrus; AG: angular gyrus; MFG: middle frontal gyrus; LG: lingual gyrus.