Aerobic Exercise Regulates Apoptosis through the PI3K/Akt/GSK-3<i>β</i> Signaling Pathway to Improve Cognitive Impairment in Alzheimer’s Disease Mice

<div>Number of PI3K-, p-Akt-, and GSK-3<i>β</i>-positive neurons in hippocampal CA1 of each group of mice. (a–c) PI3K, P-Akt, and GSK-3<i>β</i> immunohistochemical results of the hippocampal CA1 region in each group. (d) The number of immunohistochemical-positive cells in the hippocampal CA1 area of each group. 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Scale bar: 50 <i>μ</i>m.</div>

Neural Plasticity

fig3

Figure 3

Figure 3: Aerobic Exercise Regulates Apoptosis through the PI3K/Akt/GSK-3<i>β</i> Signaling Pathway to Improve Cognitive Impairment in Alzheimer’s Disease Mice 

Figure 3 | Aerobic Exercise Regulates Apoptosis through the PI3K/Akt/GSK-3β Signaling Pathway to Improve Cognitive Impairment in Alzheimer’s Disease Mice 