Influence of High-Frequency Repetitive Transcranial Magnetic Stimulation on Neurobehavioral and Electrophysiology in Patients with Disorders of Consciousness

Table 2

Comparison measured parameters at baseline and postintervention in the active and sham groups.

Variable	Baseline	Postintervention	value	95% CI
CRS-R total score
Active group		9 (7.5-13)	<0.001^b	—
Sham group		8 (6 -9)	<0.001^b	—
GCS total score
Active group	8 (7-8)	8 (8-9)	<0.001^b	—
Sham group	8 (7-8)	8 (7.5-8)	0.007^b	—
Latencies of N20 component (ms)
Active group			<0.001^a	0.490, 0.900
Sham group			0.113^a	-0.040, 0.350
N20-P25 amplitudes (μV)
Active group			<0.001^a	-2.012, -1.076
Sham group			<0.001^a	-1.163, -0.422
BAEP grade (number)
Active group (grade-I/II/III/IV)	0/13/9/3	2/18/4/1	0.022^b	—
Sham group (grade-I/II/III/IV)	0/12/9/4	0/14/8/3	0.013^b	—

Data are presented as deviation or median (interquartile range). Abbreviations: CRS-R: Coma Recovery Scale-Revised; GCS: Glasgow Coma Scale; BAEP: brainstem auditory-evoked potential; CI: confidence intervals. Significance level at value < 0.05; value refers to the results of ^atwo-tailed unpaired Student’s -test and the ^bpaired Wilcoxon rank-sum test.