Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice

Table 2

t-test and Pearson’s results summary table.

t-tests
Peri-infarct		Pro-BDNF	T-mTOR	P-mTOR	T-p70S6K	P-p70S6K
	(Stoke+Saline vs. Stroke+r-hGH)	vs.	vs.	vs.	vs.	vs.
	T, df, value	4.029, 15, 0.0011	2.389, 5, 0.0305	0.4491,15, 0.7	0.9922, 15, 0.3	0.7802, 15, 0.5
Hippocampus		Pro-BDNF	T-mTOR	P-mTOR	T-p70S6K	P-p70S6K
	(Stoke+Saline vs. Stroke+r-hGH)	vs.	vs.	vs.	vs.	1 vs.
	T, df, value	3.487, 15, 0.0033	1.431, 15, 0.2	0.3006, 15, 0.8	2.429, 15, 0.0282	0.9843, 15, 0.3
Thalamus		Pro-BDNF	T-mTOR	P-mTOR	T-p70S6K	P-p70S6K
	(Stoke+Saline vs. Stroke+r-hGH)	vs.	vs.	vs.	vs.	vs.
	T, df, value	3.082, 15,	2.984, 15,	1.598, 15,	2.030, 15,	0.4560, 15,
Pearson’s correlation
Peri-infarct		Pro-BDNF and T-mTOR	Pro-BDNF and GluR1	Pro-BDNF and NeuN	Pro-BDNF and DCX
	Pearson’s	0.86	0.67	0.68	0.61
	value	<0.0001	0.0004	0.0004	0.002
Hippocampus		Pro-BDNF and t-mTOR	Pro-BDNF and GluR1	Pro-BDNF and NeuN	Pro-BDNF and DCX
	Pearson’s	0.54	0.68	0.36	0.14
	value	0.0076	0.0003	0.0882	0.5
Thalamus		Pro-BDNF and t-mTOR	Pro-BDNF and GluR1	Pro-BDNF and NeuN	Pro-BDNF and DCX
	Pearson’s	0.28	0.63	0.12	0.63
	value	0.2	0.0014	0.4	0.0013

FC = fold change; SD = standard deviation; = rho.