Apathy in Parkinson’s Disease: An Electrophysiological Study

Table 2

Characteristics distinguishing apathetic from nonapathetic patients during OFF period.

Data	Average in apathetic patients; (𝑛=10)	Average in nonapathetic patients; (𝑛=15)	𝑃	𝜌
General
Age (years)	67.4	61.9	0.0301	−2.168
Electrophysiological
Average P300a amplitude in Fz (𝜇V)	14.0	23.1	0.0592	−1.886
Cognitive
Verbal fluency (animals)	14.8	20.8	0.0113	−2.533
Verbal fluency (letter M)	5.6	12.9	0.0017	−3.146
Wisconsin (number of series)	2.8	4.7	0.0144	−2.448
Wisconsin (number of mistakes)	23.6	9.3	0.002	−3.085
Wisconsin (perseveration percentage)	36.5	19.3	0.0272	−2.209
Stroop (SR-SP)	−4.3	0.4	0.1831	−1.331
Apathy (Starkstein)	16.2	6.8	<0.001	−4.174
Thymic
HAD (depression)	8.5	3.3	0.0002	−3.68
HAD (anxiety)	10.5	8.3	0.0613	−1.872
Motor
UPDRS III (total score)	28.8	23.9	0.1561	−1.418
UPDRS III (axial score)	14.4	9.267	0.0226	−2.28

𝑃: probability; 𝜌: coefficient of correlation.