Research Article

Comparing the Expression of Genes Related to Serotonin (5-HT) in C57BL/6J Mice and Humans Based on Data Available at the Allen Mouse Brain Atlas and Allen Human Brain Atlas

Table 3

Internet databases and tools for exploring diverse neurobiological, genetic, cellular, and physiological data.

Resource (database-DB/Tool-T)Web addressPurpose

Reference atlashttp://atlas.brain-map.org/Interactive reference atlas for mice and humans

Anatomic Gene Expression Atlas – AGEA (DB/T)http://www.brain-map.org/agea/Atlas of genic expression that allows users to visualize the correlation of expression patterns between areas of interest

Brain Explorer 2 (H)http://mouse.brain-map.org/static/brainexplorerOpen-access software for visualizing the structures and expression of all mouse, human, and neurodevelopment genes

Brain Architecture Knowledge Management System (BAMS) Ontological neuroanatomical (DB)http://neuro.imm.dtu.dk/wiki/Brain_Architecture_Management_SystemDevelopment of a semantic framework for classifying types of neurons and classes

Cell Centered Database (CCDB) (DB)http://ccdb.ucsd.edu/Database of images in 2D, 3D, and 4D

Gene Expression Nervous System Atlas (GENSAT) (DB)http://www.gensat.org/Detection of the expression of genes in the mouse CNS with genetic techniques and with transgenic animals

GenePaint (DB)http://www.genepaint.org/Digital atlas of genetic expression patterns in adult mice and during development.

International Neuroinformatics Coordinating Facility (INCF) (DB)http://www.genepaint.org/Neuroinformatic tools for searching other databases and sources

NeuroMorpho (DB)http://neuromorpho.org/Digitally reconstructed neurons

NeuroGateway (DB)http://neurogateway.org/catalog/goto.do?page=.sfngatewayNeuroscience sources, data and tools

Brain Architecture Management System (BAMS) (DB)https://bams1.org/Neuronal projections in the mouse brain

Collations of Connectivity Data on the Macaque Brain (CoCoMac) (BD)http://cocomac.orgNeural projections in the macaque brain

Functional Anatomy of the Cerebro–Cerebellar System (FACCS) (DB)http://www.rbwb.org/3D atlas of axonal pathways in mice

BrainMaps.org (DB)http://brainmaps.orgInteractive brain atlases for various species

Database on connectivity in humans (DB)http://brainarchitecture.orgPostmortem study databases on connectivity in humans

Brain connectivity database (DB)http://www.cma.mgh.harvard.edu/ibcd/Database of studies on connectivity in humans.

Surface Management System DataBase (SumsDB) (DB)http://brainvis.wustl.edu/wiki/index.php/Sums:AboutAtlas showing connection density in macaques

SynapseWeb (BD)http://synapses.clm.utexas.edu/Reconstruction structures from electron microscopy images

Neocortical microcircuit database (DB)https://bbp.epfl.ch/nmc-portal/welcomeDatabase of cellular connections

Atlas ICBM DTI-81 (DB)http://www.loni.usc.edu/ICBM/Downloads/Downloads_DTI-81.shtmlAtlas of diffusion tensor imaging in humans

Anatomy Toolbox Fiber Tracts (DB)http://www.fz-juelich.de/ime/spm_anatomy_toolboxAtlas of white matter connectivity

WormAtlas (DB)http://www.wormatlas.orgAtlas of C. elegans neurons

Molecular Anatomy of the Mouse Embryo Project (MAMEP) (DB)Functional analysis of gene expression during development

EMBRYS (DB)http://integbio.jp/dbcatalog/en/record/nbdc00867Functional analysis of gene expression during development

EURExpress (DB)http://www.eurexpress.orgNeuroanatomical atlas of transcriptome development in mice

The Brain Gene Expression Map BGEM (DB)http://www.stjudebgem.orgDetect gene expression in the mouse CNS using genetic techniques and transgenic animals

Adapted from [9, 10, 36, 37].