Research Article

Medication Beliefs and Adherence to Antiseizure Medications

Table 2

Clinical variables related to epilepsy among participants assessed for medication beliefs and adherence to antiseizure medications.

ParameterTotal (N = 123)Adh (N = 96)N-Adh (N = 27) value

Comparison of epilepsy parameters by using Z-test:
Partial seizures56.5%50.0%80.0%ES = 0.52,  = 0.003
Mixed seizures13.1%16.6%0.0%ES = 0.42,  = 0.01
No group difference at 5.0% in generalized seizures, etiological types, and mean seizure frequency

Comparison of treatment parameters by using Z-test:
Valproic acid43.5%50.0%20.0%ES = 0.50,  = 0.003
Carbamazepine43.5%33.3%80.0%ES = 0.84,  = 0.001
Phenytoin13.0%16.6%0.0%ES = 0.42,  = 0.01
Othersa34.8%34.8%0.0%ES = 0.70,  = 0.0002
No significant group difference at 5.0% in polytherapy and treatment with phenobarbital

Comparison of side-effect parameters by using Z-test:
Restlessness13.0%13.0%0.0%ES = 0.40,  = 0.02
Dizziness17.4%5.5%60.0%ES = 1.5,  = 0.001
Headache26.1%22.2%40.0%ES = 0.32,  = 0.03
Fatigue43.5%38.8%60.0%ES = 0.34,  = 0.02
No significant group difference at 5.0% in parameters of weight gain, nervousness, hyperactivity, hand tremors, poor attention, drowsiness, weight loss, appetite, upset stomach, double or blurred vision, and troubles with memory, sleep, mood, skin, and mouth and gums

Note. Adh: adherent; ES: effect size; N-Adh: nonadherent; aOthers: primidone, clonazepam, lamotrigine, levetiracetam, and acetazolamide.