Research Article
Validation of an Individualized Measure of Quality of Life, Patient Generated Index, for Use with People with Parkinson’s Disease
Table 4
Comparison of the PGI against standard PRO measures at the item level among people who endorsed the area.
| | Items | Number of response options | Standard PRO measure | Agreement
Δ ± 1
N (%) | PPV (%) | NPV (%) |
| | Walking | | Walking several blocks | 3 | RAND-36 PFI | 20 (100) | 70 | 63 | | Walking one block | 3 | RAND-36 PFI | 18 (90) | 55 | 80 | | Walking more than a kilometer | 3 | RAND-36 PFI | 17 (85) | 80 | 59 |
| | Fatigue | | Energy for daily activities | 4 | AS | 16 (100) | 69 | 41 | | Much fatigue to none | 10 | VAS | 11 (69) | 94 | 33 |
| | Depression | | Much depression to no depression | 10 | VAS | 6 (75) | 86 | 63 | | Felt depressed | 5 | PDQ-8 | 3 (38) | 85 | 66 |
| | Memory/concentration | | Forget if you had already done something | 5 | PDQ-20 | 12 (80) | 80 | 75 | | Forget what you came into the room for | 5 | PDQ-20 | 11 (73) | 67 | 46 | | Trouble concentrating | 5 | PDQ-20 | 11 (73) | 53 | 70 | | Forget what you did the night before | 5 | PDQ-20 | 11 (73) | 53 | 70 | | Find your mind drifting | 5 | PDQ-20 | 11 (73) | 67 | 56 | | Forget what you did last weekend | 5 | PDQ-20 | 11 (73) | 67 | 62 | | Forget to take your medication | 5 | PDQ-20 | 11 (73) | 67 | 74 |
|
|
N, number; PPV, positive predictive value; NPV, negative predictive value; PFI, Physical Function Index; AS, Apathy Scale; VAS, visual analogue scale; PDQ-20, Perceived Deficits Questionnaire-20.
|
