| | Author (s) | Definition of an acute SSTI | Definition of SSTI treatment failure |
| | Llera et al. [68] | “Heat (calor), pain (dolor), redness (rubor), and swelling (tumor)” | Return of SSTI in the same anatomical location within 12 months | | Eryilmaz et al. [69] | “Redness, warmth, tenderness, induration, palpable mass” | SSTI recurrence | | Tsoraides et al. [70] | Not described | Continuing cellulitis and purulent drainage | | McNamara et al. [65] | Not described | Fever, cellulitis, pain | | Gaspari et al. [19] | Superficial, fluctuance, and induration | Sonographic and clinical variables, not otherwise described | | Alder et al. [64] | Not described | Not described | | Singer et al. [67] | Not described | Not described | | Winstead [71] | Not described | Not described | | Singer and Talan [72] | “A swollen, red, tender, and fluctuant mass, often with surrounding cellulitis” | Not described | | Ladde et al. [73] | Not described | Not described | | Mahida et al. [74] | Not described | Not described | | Rencher et al. [66] | “Erythema, induration or fluctuance, and tenderness” | “Worsening erythema, tenderness, induration, and/or fluctuance or patients demonstrating persistent fever and systemic illness” | | Lasithotakis et al. [32] | Not described | Not described | | Özturan et al. [75] | Not described | Pain and cellulitis | | Yang et al. [33] | “Confirm via ultrasound or fine needle aspiration”, fever, and cellulitis | Pain, fever, and cellulitis | | Long and April [76] | Not described | Reduction in cellulitis | | Schechter-Perkins et al. [21] | Not described | Erythema, warmth, tenderness, induration, fluctuance, purulence | | Zhimin et al. [77] | “Redness, discomfort, swelling, and pain” | Not described | | Gottlieb et al. [57] | Not described | Not described |
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