Endometriosis Gene Expression Heterogeneity and Biosignature: A Phylogenetic Analysis

Table 2

Gene list summarizing the biosignature of the eutopic clade.

Function	Gene symbol
Cell cycle	CDKN2A	PTGS2	EGFR	MDM2	F2
	BRCA2	BTRC
Clotting/vascular integrity	F2	NOS1	RHOA	MMP1	SP1
Cell adhesion and migration	CD36	RHOA	MMP1	EGFR	CDKN2A
	F2	JAG1	PTGS2
Apoptosis	MDM2	BAT3	BCL2L1	IL17A	RARA
	CASP3	BAD	AKAP13	PTGS2	EGFR
	CDKN2A	F2	RHOA
Infertility/fertility	MMP1	EGFR	BRCA2	BCL2L1	PTGS2
Immunity	CD19	CD68	IL17A	IL1RN	RARA
	CMA1	CDKN2A	BAD	CD36	CNR2
	MMP1
Inflammation	IL1RN	IL17A	CMA1	PTGS2	F2
	CNR2
Cell structure	KCNJ5	TPM3	RHOA	EGFR	F2
	MMP1
Carcinogenesis	TPM3	KLK3	EGFR
Angiogenesis/invasion	JAG1	KLK3	PTGS2
Cell proliferation	EGFR	CDKN2A	F2	BRCA2	MDM2
	BTRC	BAD	BCL2L1	JAG1
Organogenesis	SP1	TPM3	MMP1	EGFR	BCL2L1
	DRD2	JAG1
Steroid hormone regulation	RARA	RHOA
Tumor suppressor	MDM2	BAT3	BRCA2	NOS1
Stress response	FADS1	NOS1	RHOA
Protein ubiquitination	BTRC	MDM2
Lipid metabolism	ABCA1	FADS1	PTGS2	CD36
Dopamine receptor	DRD2
Ion transport	KCNJ5	SP1	RARA	DRD2	PTGS2
Glucose homeostasis	BAD	RHOA
Cell debris removal	CD68	CD36
Water and ion balance	DRD2
Cell differentiation	FADS1	JAG1	SP1	RHOA