Research Article
Degree and Rate of Growth Discordance in Dichorionic Twins Conceived by In Vitro Fertilization
Table 2
Type of delivery and neonatal outcome stratified by mode of conception.
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Conceived spontaneously |
Conceived by IVF |
Adjusted | Outcome | Concord 201 (93.5%) | Discord 14 (6.5%) | RR (95% CI) | value | Concord 164 (93.2%) | Discord 12 (6.8%) | RR (95% CI) | value | B-D value | CMH value | RR (95% CI) |
| PTD < 28 wks | 4 (2%) | 0 | 0.67 (0.04–11.64) | 1.0 | 5 (3%) | 1 (8%) | 0.36 (0.05–2.89) | 0.35 | 0.390 | 0.672 | 0.65 (0.09–4.87) | PTD < 34 wks | 33 (16%) | 7 (50%) | 0.33 (0.18–0.60) | 0.006 | 23 (14%) | 6 (50%) | 0.28 (0.14–0.55) | 0.005 | 0.825 | <0.001 | 0.31 (0.19–0.48) | Cesarean section | 111 (55%) | 10 (72%) | 0.77 (0.54–1.10) | 0.28 | 140 (91%) | 12 (100%) | 0.91 (0.86–0.95) | 0.38 | 0.311 | 0.078 | 0.82 (0.70–0.96) | Apgar score 5′ < 7 (either twin) | 38 (19%) | 7 (50%) | 0.38 (0.21–0.69) | 0.015 | 53 (31%) | 7 (58%) | 0.62 (0.35–1.10) | 0.11 | 0.645 | 0.001 | 0.47 (0.31–0.69) | NICU, either twin | 39 (19%) | 8 (57%) | 0.29 (0.18–0.47) | 0.003 | 55 (34%) | 8 (67%) | 0.50 (0.32–0.79) | 0.029 | 0.693 | <0.001 | 0.42 (0.30–0.59) | Composite end point | 72 (35.8%) | 11 (78.6%) | 2.5 (1.8–3.5) | 0.0001 | 60 (36.5%) | 9 (75.0%) | 2.0 (1.3–3.0) | 0.0002 | 0.701 | <0.001 | 2.2 (1.6–3.2) |
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IVF denotes in vitro fertilization; PTD, preterm delivery; NICU, neonatal intensive care unit; RR, relative risk; CI, confidence interval; B-D, Breslow-Day test; CMH, Cochran-Mantel-Haenszel test.
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