Plasma Markers of Oxidative Stress in Patients with Gestational Diabetes Mellitus in the Second and Third Trimester

Table 2

Markers of oxidative stress and antioxidants in women with GDM and without GDM (controls).

	GDM			Controls
	16–20 weeks	24–28 weeks	32–36 weeks	16–20 weeks	24–28 weeks	32–36 weeks
PCO (ng/mL)	172.77 ± 13.59	200.77 ± 19.23	232.48 ± 21.93	136.82 ± 10.05	169.09 ± 13.10	180.81 ± 11.57
AOPPs (mol/L)	64.74 ± 1.39	74.92 ± 1.67^△	83.59 ± 1.87^△	59.98 ± 1.54	65.83 ± 1.57	72.86 ± 1.34
8-iso-PGF2α (ng/mL)	196.14 ± 16.78	356.96 ± 40.10	538.72 ± 67.36	154.82 ± 9.89	289.74 ± 22.68	381.07 ± 37.26
GPX-3 (IU/mL)	160.42E3 ± 13.76E3	68.29E3 ± 8.50E3	35.65E3 ± 2.90E3^#	83.71E3 ± 25.58E3	44.590E3 ± 3.49E3	26.46E3 ± 1.46E3
PON1 (mIU/mL)	162.88E3 ± 22.12E3	136.18E3 ± 20.98E3	97.00E3 ± 5.51E3	260.20E3 ± 28.89E3	165.77E3 ± 18.92E3	115.59E3 ± 25.73E3

Data are means ± SD. ⁢ versus controls. ⁢ versus controls. ⁢ versus controls. There was no significance in PCO (), 8-iso-PGF2α (), GPX-3 (), and PON1 () in 24–28 weeks compared to the control group. Meanwhile, in 32–36 weeks, no significance was found in PON1 () compared to the controls.