|
| | Group 1: placenta creta | Group 2: no placenta creta | Chi-square or F | |
|
| Number of cases | 169 | 1661 | | |
| Placental weight (grams ±standard deviation) | 372.8 ± 183.4 | 361.2 ± 198.1 | | |
| Inflammatory lesions |
| Chronic villitis of unknown etiology | 16 (9.5%) | 216 (13.0%) | | |
| Plasma cell deciduitis | 9 (5.3%) | 81 (4.9%) | | |
| Hypoxic lesions/patterns |
| Acute |
| Meconium (histological) | 65 (38.5%) | 710 (42.7) | | |
| Villous infarction (>5% of placental parenchyma) | 24 (14.2%) | 148 (8.9%) | 5.0 | 0.025 |
| Chronic |
| Erythroblastosis of fetal blood | 32 (18.9%) | 265 (15.9%) | | |
| Hyaline necrosis, including atherosis of spiral arterioles | 11 (6.5%) | 81 (4.9%) | | |
| Patterns of chronic hypoxic placental injury | 49 (29.0%) | 334 (20.1%) | 7.3 | 0.007 |
| Preuterine | 9 (5.3%) | 84 (5.1%) | | |
| Uterine | 25 (14.8%) | 159 (9.6%) | 4.6 | 0.032 |
| Postuterine | 15 (8.9%) | 91 (5.5%) | | |
| Retroplacental hematoma | 9 (5.3%) | 108 (6.5%) | | |
| Intervillous thrombus | 37 (21.9%) | 294 (17.7%) | | |
| Shallow placental implantation |
| Membrane chorionic microcysts | 23 (13.6%) | 203 (12.2%) | | |
| Chorionic disc extravillous trophoblast microcysts | 37 (21.9%) | 264 (15.9%) | 4.0 | 0.045 |
| Maternal floor multinucleate trophoblast giant cells | 47 (27.8%) | 352 (21.2%) | 3.9 | 0.047 |
| Excessive extravillous trophoblasts in chorionic disc | 41 (24.3%) | 288 (17.3%) | 5.0 | 0.026 |
| Fetal vascular malperfusion |
| Segmental fetal vascular malperfusion | 47 (27.4%) | 330 (19.9%) | 5.9 | 0.015 |
| Segmental stromal vascular karyorrhexis | 14 (8.3%) | 100 (6.0%) | | |
| Segmental villous mineralization | 12 (7.1%) | 146 (8.8%) | | |
| Fetal vascular ectasia | 45 (26.2%) | 253 (15.2%) | 14.6 | 0.001 |
| Stem vessel obliteration | 16 (9.5%) | 135 (8.1%) | | |
| Intramural fibrin deposition | 7 (4.1%) | 124 (7.5%) | | |
| Other |
| Massive perivillous fibrin deposition (>30% of placental parenchyma) | 16 (9.5%) | 88 (5.3%) | 5.0 | 0.026 |
| Choriodecidual hemosiderosis | 10 (5.9%) | 115 (6.9%) | | |
| Villous edema | 9 (5.3%) | 141 (8.5%) | | |
| Marginal insertion of umbilical cord | 18 (10.6%) | 112 (6.7%) | | |
| Velamentous insertion of umbilical cord | 7 (4.1%) | 52 (3.1%) | | |
| Other umbilical cord abnormalities | 30 (17.7%) | 278 (16.7%) | | |
|
