Generation of Reactive Oxygen Species during Apoptosis Induced by DNA-Damaging Agents and/or Histone Deacetylase Inhibitors

Table 2

(a) P values of one-way ANOVA of individual drugs action. (b) P values of “drug” parameter of two-way ANOVA for combined treatments.

(a)

Cell type	CML-T1	PBL
Drug
Actinomycin D	<0,0001	0,12
Sodium butyrate	0,03	0,38
SAHA	0,003	0,08
Decitabine	0,16	0,34

(b)

Cell type	CML-T1	PBL
Combination
ActD + BUT	0,03	0,74
ActD + SAHA	0,04	0,74
DAC + SAHA	0,003	0,52